Article
Details
Citation
Carroll D, Phillips AC, Thomas GN, Gale CR, Deary I & Batty GD (2009) Generalized Anxiety Disorder Is Associated with Metabolic Syndrome in the Vietnam Experience Study. Biological Psychiatry, 66 (1), pp. 91-93. https://doi.org/10.1016/j.biopsych.2009.02.020
Abstract
Background
Few studies have explored the relationship between major mental health disorders and metabolic syndrome (MetS), although both have been linked to cardiovascular disease. The present study examined the cross-sectional associations of major depressive disorder (MDD) and generalized anxiety disorder (GAD) with MetS in a large study of male US veterans.
Methods
The analyses were cross-sectional. Participants (n = 4256) were drawn from the Vietnam Experience Study. From military service files, telephone interviews, and a medical examination, occupational, socio-demographic, and health data were collected. One-year prevalence of MDD and GAD was determined with DSM-III criteria. Metabolic syndrome was ascertained from data on: body mass index, fasting blood glucose or a diagnosis of diabetes, blood pressure, high-density lipoprotein cholesterol, and triglyceride levels.
Results
In models that adjusted for age (p = .01) and additionally for place of service, ethnicity, marital status, smoking, alcohol consumption, IQ at enlistment, household income in midlife, and education grade achieved (p = .02), GAD was positively associated with MetS. Major depressive disorder was not related to MetS.
Conclusions
Depression has very much been the focal condition for studies on mental health and physical health outcomes. The current data suggest that future research should perhaps pay equal attention to GAD.
Keywords
Generalized anxiety disorder; major depressive disorder; metabolic syndrome; veterans
Journal
Biological Psychiatry: Volume 66, Issue 1
Status | Published |
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Funders | |
Publication date | 01/07/2009 |
Publication date online | 02/04/2009 |
Date accepted by journal | 13/02/2009 |
URL | |
Publisher | Elsevier BV |
ISSN | 0006-3223 |
People (1)
Professor of Behavioural Medicine, Sport