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Article

COVID-19 and anxiety in pregnancy and postpartum: a longitudinal survey

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Citation

Ayers S, Meades R, Sinesi A, Cheyne H, Maxwell M, Best C, McNicol S, Alderdice F, Jomeen J, Shakespeare J & MAP Study Team (2025) COVID-19 and anxiety in pregnancy and postpartum: a longitudinal survey. BMC Public Health, 25, Art. No.: 1146. https://doi.org/10.1186/s12889-025-22257-7

Abstract
Background Anxiety is estimated to affect between 15 and 20 per cent of women during pregnancy and postpartum. The COVID-19 pandemic resulted in wide-ranging changes to how people lived, worked and socialised around the world. COVID and pandemic-related restrictions to maternity services may have exacerbated anxiety during pregnancy and the postnatal period. This study aimed to determine: (1) levels of COVID exposure and perceived risk; (2) adherence to Government guidelines and restrictions; and (3) the impact of COVID and COVID-related restrictions on perinatal anxiety and mental health in the UK. Methods A longitudinal survey (n?=?2122) of COVID and anxiety in women during early pregnancy, mid-pregnancy, late pregnancy and postpartum. Results 38.41% of participants had COVID before or during the study. Perinatal anxiety was predicted by participants having poor general health, being of Asian or mixed ethnicity, having previous mental health problems, believing that COVID would make them severely ill, and reporting that COVID had impacted on their mental health. Over time, more women were infected with COVID, and the perceived severity of COVID decreased. Experiencing mild COVID was associated with decreased anxiety at the subsequent time point (mean difference -0.72, 95% CI -1.38 to -0.07, p?=?0.030). Very few participants in this sample had severe COVID (2.9%) or reported it having a severe impact on their mental health (5.66%). Most participants (75.3%) said the pandemic had ‘no’ or a ‘slight’ impact on their mental health. Pandemic-related restrictions to maternity care affected more women, with around 40% reporting anxiety about being separated from baby, their partner not being with them in labor, or having to leave shortly after the birth. Level of adherence to guidelines was variable, depending on the restriction. Conclusions Findings suggest pandemic-related restrictions caused anxiety for more women than COVID per se. Adherence to guidelines was variable yet the prevalence of COVID infections was low compared to the general population. Findings can be used to inform policy and practice for future pandemics and health-related crises.

Keywords
COVID-19; Pandemic; Anxiety; Pregnancy; Postpartum

Notes
MAP study Team: Georgina Constantinou, Simon Gilbody, Agnes Hann, Jennifer Holly, Grace Howard, Una Hutton, Rachael Leonard, Debra Salmon, Nazihah Uddin, James Walker, Louise R. Williams & Cassandra Yuill

Journal
BMC Public Health: Volume 25

StatusPublished
Publication date31/12/2025
Publication date online31/03/2025
Date accepted by journal10/03/2025
PublisherSpringer Science and Business Media LLC
eISSN1471-2458

People (5)

Dr Catherine Best

Dr Catherine Best

Associate Professor, Health Sciences Stirling

Professor Helen Cheyne

Professor Helen Cheyne

Personal Chair, CHeCR

Professor Margaret Maxwell

Professor Margaret Maxwell

Professor, CHeCR

Dr Stacey McNicol

Dr Stacey McNicol

Research Fellow, CHeCR

Mr Andrea Sinesi

Mr Andrea Sinesi

Research Fellow, CHeCR

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