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Citation

Stamatakis E, Wilson JTL & Wyper DJ (2000) Analysis of HMPAO SPECT scans in head injury using statistical parametric mapping. Behavioural Neurology, 12 (1-2), pp. 29-37. http://iospress.metapress.com/content/hbxttm11bqg1kcju/?p=a731f38ae31148249f8b31e9f6919a1dπ=3

Abstract
The paper examines the ability of Statistical Parametric Mapping (SPM) to contribute towards the quantitative analysis of HMPAO SPECT images containing lesions. A validation study is described in which SPECT images were created that contained synthetic lesions and were analysed with SPM. The study established a set of guidelines concerning the alignment, smoothing, and statistical analysis of images. These were then applied to analysis of SPECT scans from head injured patients. A demonstration is given of the use of SPM to identify localised blood flow abnormalities associated with cognitive deficits after head injury. Correlations between blood flow abnormalities and a test of visual memory are illustrated

Journal
Behavioural Neurology: Volume 12, Issue 1-2